Rathke’s cleft cyst is a benign cystic lesion that can affect the pituitary gland. Symptomatic Rathke’s cleft cyst (RCC), however, is relatively uncommon. When these cysts are large enough to be clinically apparent, they may cause headache, visual disturbances, nausea, decreased energy, vomiting, seizure, pituitary dysfunction, and diabetes insipidus, all due to mass effect.